Facial mesotherapy: what a course actually changes in your skin
Medical team, Nuance Clinic
Mesotherapy is often sold as a glow treatment, but its real value is cumulative dermal remodelling. This guide covers what goes into the cocktail, why a course matters, how it differs from skin boosters, and how to maintain the result.
Quick facts
- A course of 4–6 sessions is the treatment; one session is a preview.
- Improves hydration, glow, fine lines and resilience — not volume.
- NCTF 135HA is the best-documented polyrevitalising formulation.
- Maintenance every 3–6 months preserves results.
What it is
- Nutrients that cannot penetrate the skin barrier in a cream are placed exactly where fibroblasts can use them, stimulating collagen and improving the skin's water-holding capacity.
- Formulations are chosen for the problem: dullness, dehydration, early lines, acne-prone skin, hair thinning or the neck and décolleté.
Who it suits
- Dull, dehydrated, tired-looking skin
- Early fine lines and loss of bounce
- Smokers, frequent travellers and anyone with sun-stressed skin
- Also used on the scalp for hair thinning and on the neck, hands and décolleté
- Not suitable in active infection, pregnancy or known allergy to a component
Products we use
NCTF 135HA (Filorga), and other CE-approved polyrevitalising and vitamin complexes
How the treatment is performed
- Skin cleansing and topical anaesthetic for 20 minutes.
- Micro-injections in a grid pattern with a very fine needle or a controlled injector.
- Soothing mask and SPF afterwards.
Safety
- Only CE-approved, sterile, single-use ampoules are used — never decanted or mixed products of unknown origin.
- Allergy and medical history are reviewed before every course.
Before your appointment
Avoid retinoids and acids for 3 days; no active infection or fresh sunburn on the area.
Aftercare
No make-up for 12 hours, no sauna or gym for 24 hours, daily SPF, gentle cleansing for 48 hours.
Results and longevity
- Immediate glow after the first session, but the real change appears after sessions three and four.
- Best maintained with a booster every 3–6 months.
Possible side effects and risks
Redness, tiny papules for a few hours, pinpoint bruising, rare allergic reaction.
Follow-up
Photographic comparison at the end of the course and a maintenance schedule tailored to your skin.
Questions about this treatment
How many sessions do I need?
Most skin types need four to six sessions two to three weeks apart before maintenance.
Can I have it before an event?
Yes, but allow at least three days for redness and small bumps to settle.
Is it the same as skin boosters?
They overlap. Mesotherapy is nutrient-focused across a course; skin boosters place larger volumes of stabilised hyaluronic acid for longer hydration.
Ask us anything — in your language
Message the clinic on WhatsApp and get an answer from our team, not a chatbot.