NCTF 135HA: what the 'youth vaccine' does and how a course is planned
Medical team, Nuance Clinic
NCTF 135HA is one of the best-documented biorevitalisation products in aesthetic medicine. This guide explains what the 59 ingredients are for, how the injection technique differs by area, and how to combine it sensibly with toxin, filler and skin boosters.
Quick facts
- 59 actives plus free hyaluronic acid, delivered into the dermis.
- Three sessions two to three weeks apart form the base course.
- Improves radiance, firmness and fine lines; does not add volume.
- Ideal foundation treatment before filler and toxin.
What it is
- Known widely as the youth vaccine, NCTF is a mesotherapy product designed to recreate the ideal environment for fibroblasts, the cells that produce collagen and elastin.
- The free (non-cross-linked) hyaluronic acid hydrates while the active complex supports cellular metabolism.
Who it suits
- Skin that looks tired, grey or dehydrated
- Early ageing, fine crepey lines, loss of glow
- Preparation before an event, or as a foundation before filler and toxin
- Also excellent for neck, décolleté, hands and the scalp
Products we use
NCTF 135HA (Filorga) — CE-approved, sterile single-use vials
How the treatment is performed
- Cleansing and topical anaesthesia.
- Nappage micro-injection technique across the treatment zone, or point-by-point in fine-line areas.
- Post-treatment soothing and sun protection.
Safety
Original, sealed vials only; batch traceability recorded; allergy history reviewed.
Before your appointment
Pause retinoids and acids for 3 days; avoid treatment on sunburnt or infected skin.
Aftercare
No make-up for 12 hours, no heat or exercise for 24 hours, SPF daily, gentle products for 48 hours.
Results and longevity
- Glow within 48 hours of the first session; firmness and line improvement across the three-session course.
- Best results with maintenance every 3–6 months.
Possible side effects and risks
Temporary papules, redness, pinpoint bruising; rare allergic reaction.
Follow-up
Photographic review at the end of the course and a personalised maintenance interval.
Questions about this treatment
Why is it called the youth vaccine?
Because of the injection technique and the idea of dosing the skin with the nutrients it needs — it is not a vaccine in the immunological sense.
Can I combine it with filler or toxin?
Yes, and it is often the ideal base treatment. Sequencing is planned at consultation.
How soon before a wedding?
Finish the course at least two weeks before the event, ideally starting three months ahead.
Ask us anything — in your language
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