HarmonyCa: how a hybrid injectable lifts and stimulates collagen at the same time
Medical team, Nuance Clinic
HarmonyCa sits between filler and biostimulator, and it needs to be understood as both. This guide explains the two components, the injection planes, the timeline of the collagen phase, and which faces genuinely benefit from it.
Quick facts
- Hyaluronic acid for immediate lift, calcium hydroxylapatite for collagen.
- Mid-face and jawline only; never lips or tear troughs.
- Result builds from week 6 and can last 18–24 months.
- Partly non-reversible — placement discipline is essential.
What it is
- A hybrid injectable licensed for sub-dermal placement in the mid-face and along the jawline, delivering the immediate effect of a filler with the biostimulatory effect of calcium hydroxylapatite.
- It suits patients who want lift and skin-quality improvement in one procedure rather than layering treatments over months.
Who it suits
- Mid-face descent, flattening cheeks, early jowl formation
- Loss of jawline definition with mild skin laxity
- Patients who want fewer appointments
- Not for lips, tear troughs or very thin superficial skin
Products we use
HarmonyCa and HarmonyCa Lidocaine (Allergan Aesthetics) — CE-approved
How the treatment is performed
- Facial analysis, marking of the injection vectors and photography.
- Cannula or needle placement in the deep subcutaneous plane.
- Post-injection moulding to the planned contour.
Safety
- The calcium hydroxylapatite component is not reversible; depth and plane discipline are essential.
- Only injected by the doctor, in appropriate anatomical zones.
Before your appointment
Avoid blood thinners where medically allowed; no active infection; plan 5 days before an event.
Aftercare
No massage unless instructed; no gym, sauna or dental work for 48 hours; sleep elevated for two nights.
Results and longevity
- Immediate lift, a settling phase over 2 weeks, then progressive firmness from week 6 as collagen forms.
- Combined effect commonly lasts 18–24 months.
Possible side effects and risks
Swelling, bruising, tenderness, nodules if misplaced, rare vascular complications.
Follow-up
Review at 6–8 weeks to assess the collagen phase and decide whether a second syringe is needed.
Questions about this treatment
How is it different from normal filler?
Normal hyaluronic acid filler only fills. HarmonyCa also stimulates collagen, so part of the result is your own tissue.
Can it be dissolved?
The hyaluronic acid part can, the calcium hydroxylapatite part cannot. That is why plane and quantity discipline matter.
Is it a facelift?
No. It lifts and firms moderately; significant skin laxity needs surgical or energy-based treatment.
Ask us anything — in your language
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